• Ann Tieleman, Karel Deblaere, Dirk Van Roost, Olivier Van Damme, and Eric Achten.
• Department of Neuroradiology, Ghent University Hospital, Ghent, Belgium. Ann.tieleman@ugent.be
• Eur Radiol. 2009 Oct 1;19(10):2523-34.

AbstractMinimally invasive resection of brain tumours aims at removing as much pathological tissue as possible while preserving essential brain functions. Therefore, the precise spatial relationship between the lesion and adjacent functionally essential brain parenchyma needs to be known. Functional magnetic resonance imaging (fMRI) is increasingly being used for this purpose because of its non-invasiveness, its relatively high spatial resolution and the preoperative availability of the results. In this review, the goals of fMRI at various key points during the management of patients with a brain tumour are discussed. Further, several practical aspects associated with fMRI for motor and language functioning are summarised, and the validation of the fMRI results with standard invasive mapping techniques is addressed. Next, several important pitfalls and limitations that warrant careful interpretations of the fMRI results are highlighted. Finally, two important future perspectives of presurgical fMRI are emphasised.

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