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Ugeskrift for laeger · Nov 1998
Case Reports[Toxic epidermal necrolysis after treatment with lamotrigine].
- C O Zachariae and K Fogh.
- Dermatologisk afdeling, Bispebjerg Hospital, København.
- Ugeskr. Laeg. 1998 Nov 9;160(46):6656-7.
AbstractA case of toxic epidermal necrolysis following treatment with lamotrigine is presented. A 20 year old male suffering from epilepsy was treated with lamotrigine in addition to valproic acid. After three weeks he developed cutaneous manifestations of Steven-Johnson's syndrome followed by toxic epidermal necrolysis, mucosal lesions and liver symptoms. He was treated with systemic corticosteroids, antibiotics and intravenous fluid, and recovered after a few weeks.
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