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- William H Frishman and Wilbert S Aronow.
- Department of Medicine, New York Medical College, Westchester Medical Center, Valhalla, NY 10595, USA. William_Frishman@nymc.edu
- Clin. Geriatr. Med. 2012 Nov 1; 28 (4): 575-615.
AbstractBradyarrhythmias and tachyarrhythmias are common in elderly patients as a result of aging and acquired cardiac disease. Antiarrhythmic drugs are effective in elderly patients for the management of supraventricular and ventricular arrhythmias; however, dosing of drugs must be performed with care because of age-related changes in drug pharmacokinetics, the presence of concomitant disease, and frequent drug-drug interactions. Despite the large number of antiarrhythmic drugs having different electrophysiologic actions, as described in this article, only the β-blockers have been shown to be effective in reducing mortality and to lack proarrhythmic actions.Copyright © 2012 Elsevier Inc. All rights reserved.
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