• Pediatr. Clin. North Am. · Oct 1998

    Review Case Reports

    Alpha 2 adrenergic agonists. Neurochemistry, efficacy, and clinical guidelines for use in children.

    • J H Newcorn, K Schulz, M Harrison, M D DeBellis, J K Udarbe, and J M Halperin.
    • Division of Child and Adolescent Psychiatry, Mount Sinai Medical Center, New York, New York, USA.
    • Pediatr. Clin. North Am. 1998 Oct 1; 45 (5): 1099-22, viii.

    AbstractThe alpha 2 adrenergic agonists are used to treat a variety of psychiatric disorders and their usage has been increasing. This article presents the rationale and neurochemical basis for treatment of psychiatric disorders with alpha 2 agents, reviews studies examining clinical efficacy, and develops guidelines for usage. Case vignettes are presented to illustrate how the alpha 2 agents can successfully be used in practice.

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