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- James M Backes, Patrick M Moriarty, Janelle F Ruisinger, and Cheryl A Gibson.
- Department of Pharmacy Practice, Kansas University Medical Center, Kansas City, Kansas, USA.
- Am. J. Cardiol. 2007 Aug 1; 100 (3): 554-5.
AbstractStatins possess an excellent safety profile and are generally well tolerated when administered in the standard once-daily dosing regimen. A small percentage of patients however, discontinue therapy because of adverse events such as myalgias. The investigators describe 8 patients with previous intolerance to daily statin dosing and examine their responses to once-weekly rosuvastatin therapy. In conclusion, once-weekly rosuvastatin may be a feasible and effective option for patients previously intolerant to once-daily statin dosing.
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