• M A Bodí, T Pont, A Sandiumenge, E Oliver, J Gener, M Badía, J Mestre, E Muñoz, X Esquirol, M Llauradó, J Twose, and S Quintana.
• Servicio de Medicina Intensiva, Hospital Universitario de Tarragona Joan XXIII, Universitat Rovira i Virgili, Institut Investigació Sanitària Pere Virgili, Tarragona, España. Electronic address: mbodi.hj23.ics@gencat.cat.
• Med Intensiva. 2015 Aug 1; 39 (6): 337-44.

ObjectiveTo analyze the profile, incidence of life support therapy limitation (LSTL) and donation potential in neurocritical patients.Study DesignA multicenter prospective study was carried out.SettingNine hospitals authorized for organ harvesting for transplantation.PatientsAll patients consecutively admitted to the hospital with GCS < 8 during a 6-month period were followed-up until discharge or day 30 of hospital stay.Study VariablesDemographic data, cause of coma, clinical status upon admission and outcome were analyzed. LSTL, brain death (BD) and organ donation incidence were recorded.ResultsA total of 549 patients were included, with a mean age of 59.0 ± 14.5 years. The cause of coma was cerebral hemorrhage in 27.0% of the cases.LSTL was applied in 176 patients (32.1%). In 78 cases LSTL consisted of avoiding ICU admission. Age, the presence of contraindications, and specific causes of coma were associated to LSTL. A total of 58.1% of the patients died (n=319). One-hundred and thirty-three developed BD (24.2%), and 56.4% of these became organ donors (n=75). The presence of edema and mid-line shift on the CT scan, and transplant coordinator evaluation were associated to BD. LSTL was associated to a no-BD outcome. Early LSTL (first 4 days) was applied in 9 patients under 80 years of age, with no medical contraindications for donation and a GCS ≤ 4 who finally died in asystole.ConclusionsLSTL is a frequent practice in neurocritical patients. In almost one-half of the cases, LSTL consisted of avoiding admission to the ICU, and on several occasions the donation potential was not evaluated by the transplant coordinator.Copyright © 2014 Elsevier España, S.L.U. and SEMICYUC. All rights reserved.

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