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Randomized Controlled Trial Comparative Study Clinical Trial
Morphine compared with diamorphine. A comparison of dose requirements and side-effects after hip surgery.
- S L Robinson, D J Rowbotham, and G Smith.
- University Department of Anaesthesia, Leicester Royal Infirmary.
- Anaesthesia. 1991 Jul 1; 46 (7): 538-40.
AbstractThe dose requirements and side effects of morphine were compared with those of diamorphine administered by patient-controlled analgesia in 40 patients following elective total hip replacement. Patients were allocated randomly to receive in a double-blind manner either morphine or diamorphine for postoperative pain relief. There were no significant differences between the two groups with regard to postoperative sedation, nausea, well-being, pain relief and requirements for antiemetic drugs. The dose requirement for diamorphine was approximately 50% of that for morphine.
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