• Diabetes Res. Clin. Pract. · Dec 2012

    C-peptide response to glucagon challenge is correlated with improvement of early insulin secretion by liraglutide treatment.

    • Michinori Takabe, Tomokazu Matsuda, Yushi Hirota, Naoko Hashimoto, Tomoaki Nakamura, Kazuhiko Sakaguchi, Wataru Ogawa, and Susumu Seino.
    • Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
    • Diabetes Res. Clin. Pract. 2012 Dec 1; 98 (3): e32-5.

    AbstractThe amelioration of glucose tolerance by liraglutide was associated with a significant improvement of early insulin-response during OGTT. The serum C-peptide response to glucagon challenge strongly correlated with the improvement of the early insulin-response. The C-peptide response to glucagon challenge would be useful to predict therapeutic response to liraglutide.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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