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Randomized Controlled Trial Clinical Trial
IV lignocaine fails to attenuate the cardiovascular response to laryngoscopy and tracheal intubation.
- C D Miller and S J Warren.
- Grantham Hospital, Aberdeen, Hong Kong.
- Br J Anaesth. 1990 Aug 1; 65 (2): 216-9.
AbstractI.v. lignocaine has been used with varying success to attenuate the cardiovascular responses to laryngoscopy and tracheal intubation. We determined the optimal time of administration in 45 ASA I and II Chinese patients premedicated with morphine and hyoscine, and anaesthetized with thiopentone and suxamethonium. Patients were allocated randomly to a control group or three treatment groups to receive lignocaine 1.5 mg kg-1 i.v. 1, 2, or 3 min before laryngoscopy. Analysis of variance for measured and derived cardiovascular variables failed to show any significant difference between any of the groups.
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