• Indian pediatrics · Jul 2015

    Russells Viper Envenomation-associated Acute Kidney Injury in Children in Southern India.

    • Sriram Krishnamurthy, Kuralvanan Gunasekaran, Subramanian Mahadevan, Zachariah Bobby, and Ajith Prabhu Kumar.
    • Departments of Pediatrics, *Biochemistry and #Community Medicine; Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India. Correspondence to: Dr. Subramanian Mahadevan, Professor, Department of Pediatrics, JIPMER, Puducherry 605 006, India. mahadevan.subramanian80@gmail.com.
    • Indian Pediatr. 2015 Jul 1; 52 (7): 583-6.

    ObjectiveTo determine the frequency and risk factors of acute kidney injury in children with Russells viper envenomation using Acute Kidney Injury Network definition and classification system.MethodsA prospective observational study recruiting 61 subjects managed as per the National Snakebite Protocol.Results45.9% of envenomed children had acute kidney injury. The median (IQR) of the maximum serum creatinine level during hospitalization was 2 (1.3-4.8) mg/dL. The distribution of stages 1, 2 and 3 of acute kidney injury was 32.1%, 17.9% and 50% respectively. Dialysis was required in 35.7% of the children with acute kidney injury.ConclusionAcute kidney injury is common with Russells viper envenomation. Native treatments and bleeding manifestations were associated with acute kidney injury in our patient population.

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