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Anasth Intensivther Notfallmed · Jan 1990
Clinical Trial Controlled Clinical Trial[The modification of injection pain and the incidence of thrombophlebitis following etomidate].
- I Rühmann and C Maier.
- Zentrale Abteilung für Anästhesiologie des Klinikums der Christian-Albrechts-Universität Kiel.
- Anasth Intensivther Notfallmed. 1990 Jan 1; 25 Suppl 1: 31-3.
AbstractA prospective study with 161 patients was performed to investigate the effects of intravenous local anaesthetics on the pain of injection following etomidate injection. After placebo injection 56.6% of the patients reported on pain after etomidate, but only 29% after 20 mg lidocaine i.v. Lidocaine combined with venous congestives significantly reduced the incidence of pain to 3.35%. A dilution of etomidate with water (ratio 1:1) had a lower effect (17.6% incidence of pain). The rate of postoperative thrombophlebitis was lowest in the group with combined lidocaine with venous congestives at 7.4%, in opposition to a rate of 18% in the remaining groups. In comparison to a second contralateral venous cannula without applied etomidate the venous sequelae did not increase significantly.
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