• Daniel Heise, Daniela Sundermann, Anselm Braeuer, and Michael Quintel.
• Department of Anesthesiology, Emergency and Intensive Care Medicine, University Hospital Goettingen, Goettingen, Germany. dheise1@gwdg.de
• Eur J Cardiothorac Surg. 2010 Mar 1; 37 (3): 710-6.

ObjectivePreoperative assessment of risk factors for postoperative acute renal failure (ARF) is a key point in the management of cardiac surgery patients. A reliable evaluation of individual risk permits the efficient application of prophylactic and therapeutic measures to patients with increased risk of ARF. In 2005, Thakar published a scoring system to determine the ARF risk prior to surgery. The score allowed calculation of the incidence of postoperative ARF requiring dialysis (ARF-D) with a high level of precision.MethodsIn order to examine the reproducibility of the results on different patient populations, we retrospectively applied the scoring system to 3,508 cardiac surgery patients at the Goettingen University Hospital.ResultsWe found a qualitative correlation between the score value and ARF-D, but prognostic significance, when judged by the area under the receiver operating characteristic (ROC) curve, was considerably reduced. Also, the incidence of ARF-D in the Goettingen population was remarkably higher than the incidence shown by Thakar for patients with the same score.ConclusionsThe correlation between score values and incidence of ARF-D shows that the Thakar score is qualitatively transferable to cardiac surgery patients from other centres. Though the score allows the discrimination between patients with higher or lower risks of ARF-D within the Goettingen collective, it was not suitable to estimate the real incidence of postoperative ARF-D with sufficient precision.Copyright (c) 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

16 keywords...

hide…