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- Dereddi Raja S Reddy, Pramod K Guru, Melissa M Blessing, James R Stubbs, Alejandro A Rabinstein, and Eelco F M Wijdicks.
- Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW RO_OL_2_115CCS, Rochester, MN, 55905, USA, reddy.dereddiraja@mayo.edu.
- Neurocrit Care. 2015 Oct 1; 23 (2): 259-61.
BackgroundA 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin.MethodsCase report.ResultsRespiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway pressure (BiPAP) to intubation. Pulmonary function tests improved during this episode.ConclusionsIVIG may cause TRALI and due to subtle clinical findings can be mistaken for neuromuscular respiratory failure.
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