Opioid analgesia for infants in the neonatal intensive care

Clinics in perinatology · Sep 2002

Review

Opioid analgesia for infants in the neonatal intensive care unit.

There is an ethical obligation to relieve the pain and suffering in newborn infants. Opioids have been demonstrated to blunt the physiologic effects of pain and may prevent some of the clinical consequences of unmanaged pain. There are sufficient data to recommend the clinical use of opioid analgesics for the treatment of pain in the neonate. ⋯ Adverse effects can be minimized by the use of various drug administration techniques and close monitoring. Further research is needed to determine how to optimize their effects. Data on the long-term effects of neonatal opioid exposure are warranted.

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- Anna Taddio.
- Neonatal Intensive Care Unit, Research Institute, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada. anna.taddio@sickkids.ca
- Clin Perinatol. 2002 Sep 1; 29 (3): 493-509.
AbstractThere is an ethical obligation to relieve the pain and suffering in newborn infants. Opioids have been demonstrated to blunt the physiologic effects of pain and may prevent some of the clinical consequences of unmanaged pain. There are sufficient data to recommend the clinical use of opioid analgesics for the treatment of pain in the neonate. Neonates exposed to opioid analgesics can experience adverse effects. Adverse effects can be minimized by the use of various drug administration techniques and close monitoring. Further research is needed to determine how to optimize their effects. Data on the long-term effects of neonatal opioid exposure are warranted.

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Opioid analgesia for infants in the neonatal intensive care unit.

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