• J. Vasc. Surg. · Dec 2014

    An early validation of the Society for Vascular Surgery lower extremity threatened limb classification system.

    • David L Cull, Ginger Manos, Michael C Hartley, Spence M Taylor, Eugene M Langan, John F Eidt, and Brent L Johnson.
    • Department of Surgery, University of South Carolina School of Medicine-Greenville, Greenville Health System/University Medical Center, Greenville, SC. Electronic address: dcull@ghs.org.
    • J. Vasc. Surg. 2014 Dec 1; 60 (6): 1535-41.

    ObjectiveThe Society for Vascular Surgery (SVS) recently established the Lower Extremity Threatened Limb Classification System, a staging system using Wound characteristic, Ischemia, and foot Infection (WIfI) to stratify the risk for limb amputation at 1 year. Although intuitive in nature, this new system has not been validated. The purpose of the following study was to determine whether the WIfI system is predictive of limb amputation and wound healing.MethodsBetween 2007 and 2010, we prospectively obtained data related to wound characteristics, extent of infection, and degree of postrevascularization ischemia in 139 patients with foot wounds who presented for lower extremity revascularization (158 revascularization procedures). After adapting those data to the WIfI classifications, we analyzed the influence of wound characteristics, extent of infection, and degree of ischemia on time to wound healing; empirical Kaplan-Meier survival curves were compared with theoretical outcomes predicted by WIfI expert consensus opinion.ResultsOf the 158 foot wounds, 125 (79%) healed. The median time to wound healing was 2.7 months (range, 1-18 months). Factors associated with wound healing included presence of diabetes mellitus (P = .013), wound location (P = .049), wound size (P = .007), wound depth (P = .004), and degree of ischemia (P < .001). The WIfI clinical stage was predictive of 1-year limb amputation (stage 1, 3%; stage 2, 10%; stage 3, 23%; stage 4, 40%) and wound nonhealing (stage 1, 8%; stage 2, 10%; stage 3, 23%; stage 4, 40%) and correlated with the theoretical outcome estimated by the SVS expert panel.ConclusionsThe theoretical framework for risk stratification among patients with critical limb ischemia provided by the SVS expert panel appears valid. Further validation of the WIfI classification system with multicenter data is justified.Copyright © 2014 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

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