• Middle East J Anaesthesiol · Oct 2003

    Randomized Controlled Trial Comparative Study Clinical Trial

    Effects of sevoflurane versus TIVA on gastric intramucosal pH and hemodynamic status in colon cancer surgery.

    • Ziya Salihoğlu, Sener Demiroluk, Emre Görgün, Saffet Karaca, and Faik Ozçelik.
    • University of Istanbul, Cerrahpasa Medical Faculty, Department of Anesthesia, Istanbul, Turkey. zsalihoglu@yahoo.com
    • Middle East J Anaesthesiol. 2003 Oct 1; 17 (3): 359-69.

    BackgroundGastric tonometry is a minimally invasive device by which the adequacy of splanchnic blood flow is assessed indirectly. Patients undergoing major abdominal surgery are under the risk of developing splanchnic ischemia. The aim of this study was to compare gastric intramucosal pH and hemodynamic effects between sevoflurane and TIVA achieved by propofol.MethodsForty patients of ASA I-II were studied. Twenty patients received sevoflurane (Group S) and 20 patients received TIVA by propofol (Group P). Continuous measurements were made at four intervals: (a) 30 minutes before the starting of the surgery, (b) at the first hour of the surgery, (c) at the second hour of the surgery, (d) at the first hour after ending of the surgery. The mean arterial pressure, heart rate, SpO2, EtCO2, body temperature, central venous pressure, urine output, intramucosal and arterial pH were monitored.ResultsThere were no significant differences between two groups regarding the studied parameters.ConclusionsSevoflurane and propofol did not cause any significant difference in hemodynamic effects and splanchnic circulation measured by gastric tonometry in ASA I-II patients operated on for colon cancer.

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