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Case Reports
Systemic ropivacaine toxicity from a peripheral nerve infusion in a medically complex patient.
- Eliot Grigg, Corrie Anderson, Martha Pankovich, Lizabeth Martin, and Sean Flack.
- Department of Anesthesiology and Pain Medicine, University of Washington, Seattle Children's Hospital, 4800 Sand Point Way NE, MS 9824, Seattle, WA 98105. Electronic address: eliot.grigg@seattlechildrens.org.
- J Clin Anesth. 2015 Jun 1;27(4):338-40.
AbstractThis is a case of systemic ropivacaine toxicity from a sciatic nerve catheter. A 20-year-old patient after heart transplant with poor systemic perfusion on hemodialysis and multiple medications experienced local anesthetic systemic toxicity 72 hours after placement of a peripheral nerve catheter. The case demonstrates the potentially significant impact of medical comorbidities on system absorption of local anesthetics and reinforces that existing dose guidelines are not evidence based, and literature to guide local anesthetic bolus supplementation of continuous infusions is scant.Copyright © 2015 Elsevier Inc. All rights reserved.
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