• World J. Gastroenterol. · Oct 2014

    Case Reports

    Complete response to sorafenib in a patient with recurrent hepatocellular carcinoma.

    • Hong-Bo Huan, Wan-Yee Lau, Feng Xia, Kuan-Sheng Ma, and Ping Bie.
    • Hong-Bo Huan, Wan-Yee Lau, Feng Xia, Kuan-Sheng Ma, Ping Bie, Institute of Hepatobiliary Surgery, Southwest Hospital, Southwest Cancer Center, Third Military Medical University, Chongqing 400038, China.
    • World J. Gastroenterol. 2014 Oct 21; 20 (39): 14505-9.

    AbstractPartial hepatectomy is still the treatment of choice aiming at a cure for patients with hepatocellular carcinoma (HCC), provided that the patient can tolerate the treatment. For patients with multiple recurrent HCC after partial hepatectomy which cannot be treated by re-hepatectomy or local ablative therapy, the prognosis is extremely poor. Sorafenib is a molecular-targeted agent which has been demonstrated in two global phase III randomized controlled trials to show survival benefit for advanced HCC. Here, we present a 56-year-old patient with HCC who showed complete clinical response after sorafenib was used for tumor recurrence which developed 3 mo after partial hepatectomy. There was no evidence of progression of disease for 60 mo till now after continuous treatment with sorafenib.

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