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Diabetes Res. Clin. Pract. · Sep 2011
Atrial Natriuretic Peptide (ANP) in early pregnancy is associated with development of preeclampsia in type 1 diabetes.
- Lene Ringholm, Ulrik Pedersen-Bjergaard, Birger Thorsteinsson, Frans Boomsma, Peter Damm, and Elisabeth R Mathiesen.
- Center for Pregnant Women with Diabetes, Rigshospitalet, University of Copenhagen, Denmark. enel@dadlnet.dk
- Diabetes Res. Clin. Pract. 2011 Sep 1; 93 (3): e106-9.
AbstractThe vasoactive markers of cardiac overload Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) are elevated in preeclampsia. This study documents higher ANP concentrations as early as at 9 weeks in type 1 diabetic women subsequently developing preeclampsia suggesting that preeclampsia is associated with cardiovascular changes in early pregnancy.Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
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