• Am J Hosp Palliat Care · Sep 2013

    Case Reports

    Considering symptomatic spinal epidural lipomatosis in the differential diagnosis.

    • Adriana Alvarez, Raghava Induru, and Ruth Lagman.
    • The Harry R. Horvitz Center Section of Palliative Medicine and Supportive Oncology, Cleveland Clinic, Cleveland, OH 44195, USA.
    • Am J Hosp Palliat Care. 2013 Sep 1; 30 (6): 617-9.

    AbstractSpinal epidural lipomatosis (SEL) is the abnormal accumulation of normal fat within the spinal canal. It is more frequent in those patients receiving chronic glucocorticoid therapy or in cases of endogenous hypercortisolism states. We report a case of SEL in a patient with metastatic prostate cancer with history of steroid treatment as part of his chemotherapy regimen, presenting with clinical manifestations of partial cord compression. Magnetic resonance imaging images of the lumbar spine revealed the presence of epidural tumor suspicious for metastatic disease. Operative findings were consistent with epidural lipomatosis. Spinal epidural lipomatosis is a rare condition that needs to be included in the differential diagnosis of patients with risk factors, presenting with symptomatic cord compression.

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