• Diabetes Res. Clin. Pract. · Mar 2014

    Multicenter Study Observational Study

    Prevalence and clinical implications of painful diabetic peripheral neuropathy in type 2 diabetes: results from a nationwide hospital-based study of diabetic neuropathy in Korea.

    • Sang Soo Kim, Jong Chul Won, Hyuk Sang Kwon, Chong Hwa Kim, Ji Hyun Lee, Tae Sun Park, Kyung Soo Ko, and Bong Yun Cha.
    • Department of Internal Medicine, Pusan National University Hospital, Busan, South Korea.
    • Diabetes Res. Clin. Pract. 2014 Mar 1; 103 (3): 522-9.

    AimsTo determine the prevalence and risk factors for painful diabetic peripheral neuropathy (PDPN) and evaluate sleep impairment and quality of life in patients with PDPN.MethodsData from the Korean Diabetes Association Neuropathy Study Group were used to evaluate 3999 patients with type 2 diabetes. PDPN was diagnosed using visual analogue scales (VAS) and medical history. The patients were asked to answer the Brief Pain Inventory-Short Form (BPI-SF), Medical Outcomes Study Sleep (MOS-Sleep) Scale, EuroQol (EQ-5D), and VAS.ResultsAmong the patients with diabetic peripheral neuropathy (n=1338), 577 (43.1%) were diagnosed with PDPN (14.4% of all patients with type 2 diabetes). PDPN was independently associated with age, female gender, fasting plasma glucose, hypertension, and previous cerebrovascular events. All pain severity and interference measures were higher in patients with PDPN than in non-PDPN patients, and patients with PDPN reported more impaired sleep and lower EQ-5D and VAS scores.ConclusionsThe prevalence of PDPN in Koreans was comparable to that in Western populations. PDPN may impair sleep and quality of life compared with non-PDPN, and physicians should carefully consider pain symptoms in patients with diabetic peripheral neuropathy.Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

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