• Arch. Bronconeumol. · Nov 2014

    Elevated carboxyhemoglobin: sources of carbon monoxide exposure.

    • Herminia Buchelli Ramirez, Ramón Fernández Alvarez, Gemma Rubinos Cuadrado, Cristina Martinez Gonzalez, Francisco Rodriguez Jerez, and Pere Casan Clara.
    • Unidad de Gestión Clínica de Pulmón, Servicio de Neumología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
    • Arch. Bronconeumol. 2014 Nov 1; 50 (11): 465-8.

    IntroductionInhalation of carbon monoxide (CO) can result in poisoning, with symptoms ranging from mild and nonspecific to severe, or even death. CO poisoning is often underdiagnosed because exposure to low concentrations goes unnoticed, and threshold values for normal carboxyhemoglobin vary according to different authors. The aim of our study was to analyze carboxyhemoglobin (COHb) levels in an unselected population and detect sources of CO exposureMethodsIn a cross-sectional descriptive study, we analyzed consecutive arterial blood gas levels processed in our laboratory. We selected those with COHb≥2.5% in nonsmokers and ≥5% in smokers. In these cases a structured telephone interview was conducted.ResultsElevated levels of COHb were found in 64 (20%) of 306 initial determinations. Of these, data from 51 subjects aged 65±12 years, 31 (60%) of which were men, were obtained. Mean COHb was 4.0%. Forty patients (78%) were non-smokers with mean COHb of 3.2%, and 11 were smokers with COHb of 6.7%. In 45 patients (88.2%) we detected exposure to at least one source of ambient CO other than cigarette smoke.ConclusionsA significant proportion of individuals from an unselected sample had elevated levels of COHb. The main sources of CO exposure were probably the home, so this possibility should be explored. The population should be warned about the risks and encouraged to take preventive measures.Copyright © 2013 SEPAR. Published by Elsevier Espana. All rights reserved.

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