• Chuanzhong Yang, Xiaoyu Zhu, Weibin Lin, Qianshen Zhang, Jinqiong Su, Bingchun Lin, Hongmao Ye, and Renjie Yu.
• Neonatal Department, Shenzhen Maternal and Child Healthcare Hospital Affiliated to Southern Medical University, No.2004 Hong Li Road, Futian District, Shenzhen, 518028, China. yangczgd@163.com.
• Bmc Pediatr. 2016 Jan 25; 16: 17.

BackgroundThis study aimed to study the feasibility, efficacy and safety of using laryngeal mask (LM) ventilation compared with endotracheal intubation (ETI) during neonatal resuscitation.MethodsNeonates with a heart rate below 60 beats per minute despite 30 s of face mask ventilation were assigned quasi-randomly (odd/even birth date) to LM (n = 36) or ETI (n = 32) ventilation. Differences in first attempt insertion success, insertion time, Apgar score, resuscitation outcome, and adverse effects were compared.ResultsThere were no significant differences in first attempt at successful insertion (LM, 94.4 % vs. ETI, 90.6 %), insertion time (LM, 7.58 ± 1.16 s vs. ETI, 7.89 ± 1.52 s), Apgar score at 1 and 5 min, response time, ventilation time, successful resuscitation (LM, 86.1 % vs. ETI,  96.9 %), and adverse events (LM, n =3 vs. ETI, n =4) between groups.ConclusionsLaryngeal mask ventilation is an effective alternative to endotracheal intubation during resuscitation of depressed newborns who do not respond to face-mask ventilation. During an emergency, laryngeal mask ventilation may be a preferred technique for medical staff who are unable to acquire or maintain endotracheal intubation skills.Trial RegistrationCurrent Controlled Trials ChiCTR-IOQ-15006488. Registered on 2 June 2015.

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