• Yong-cai Hu, Cai-sheng Ou, Ze-chun Huang, Xi-sheng Xu, Zhi-xiang Li, and Liang-ying Luo.
• Department of Burns and Plastic Surgery, The First People's Hospital of Bingzhou City, Bingzhou 423000, PR China. czlizhixiang@163.com
• Zhonghua Shao Shang Za Zhi. 2006 Feb 1; 22 (1): 57-60.

ObjectiveTo observe the effectiveness of MEBO in the treatment of burn patients with burn area over 50% TBSA.MethodsTwo hundred and ninety-eight patients hospitalized in our hospital from May of 1991 to December of 2003 with burn area over 50% TBSA, who had MEBO treatment before hospitalization, were enrolled in the study as the experiment (E) group. Another group of 300 burn patients with burn area over 50% TBSA that treated with SD-Ag cream were enrolled in the study as the control (C) group. Bacterial culture results, major changes in injury and mortality were compared between the two groups.ResultsThere were 1 506 bacteria strains isolated from wounds in E group, and 9 main changes in injury (1679 cases) occurred with 20.8% mortality in this group. There were 353 bacteria strains isolated, with occurrence of 9 changes in injury (518 cases) and 4.7% mortality in the SD-Ag group.ConclusionMEBO is much less effective for the treatment of the burn patients with large burn area compared with SD-Ag cream treatment.

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