• Y Mehta, N Jaggi, V D Rosenthal, C Rodrigues, S K Todi, N Saini, F E Udwadia, A Karlekar, V Kothari, S N Myatra, M Chakravarthy, S Singh, A Dwivedy, N Sen, and S Sahu.
• Medanta The Medicity, New Delhi, India.
• Epidemiol. Infect. 2013 Dec 1; 141 (12): 2483-91.

AbstractWe report on the effect of the International Nosocomial Infection Control Consortium's (INICC) multidimensional approach for the reduction of ventilator-associated pneumonia (VAP) in adult patients hospitalized in 21 intensive-care units (ICUs), from 14 hospitals in 10 Indian cities. A quasi-experimental study was conducted, which was divided into baseline and intervention periods. During baseline, prospective surveillance of VAP was performed applying the Centers for Disease Control and Prevention/National Healthcare Safety Network definitions and INICC methods. During intervention, our approach in each ICU included a bundle of interventions, education, outcome and process surveillance, and feedback of VAP rates and performance. Crude stratified rates were calculated, and by using random-effects Poisson regression to allow for clustering by ICU, the incidence rate ratio for each time period compared with the 3-month baseline was determined. The VAP rate was 17.43/1000 mechanical ventilator days during baseline, and 10.81 for intervention, showing a 38% VAP rate reduction (relative risk 0.62, 95% confidence interval 0.5-0.78, P = 0.0001).

17 keywords...

hide…