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Arch. Gynecol. Obstet. · Aug 2014
Case ReportsVulvodynia and proctodynia treated with topical baclofen 5 % and palmitoylethanolamide.
- Jan M Keppel Hesselink, David J Kopsky, and Nancy L Sajben.
- Institute for Neuropathic Pain, Spoorlaan 37a, 3735 MV, Bosch en Duin, The Netherlands, jan@neuropathie.nu.
- Arch. Gynecol. Obstet. 2014 Aug 1; 290 (2): 389-93.
BackgroundThe prevalence of idiopathic vulvodynia and proctodynia is high. Pain management with anti-depressants and anti-epileptics may induce undesirable side effects. Therefore, topical baclofen cream and palmitoylethanolamide might be new therapeutic options.CaseA 33-year-old woman with intractable chronic vulvar and anal pain had to abstain from sexual intercourse and could neither cycle nor sit for more than 5 min. The patient did not respond to standard treatments. We prescribed a combination of topical baclofen 5 % and palmitoylethanolamide 400 mg, three times daily. After 3 months her symptoms decreased more than 50 % and sexual intercourse was possible again without pain.ConclusionTopical baclofen and palmitoylethanolamide can be a viable treatment option in chronic vulvodynia and proctodynia.
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