• J Vet Emerg Crit Care (San Antonio) · Jun 2009

    Case Reports

    Critical illness-related corticosteroid insufficiency in a dog with septic shock.

    • Jamie L Peyton and Jamie M Burkitt.
    • Department of Surgical and Radiological Sciences, William R. Pritchard Veterinary Medical Teaching Hospital, University of California Davis, Davis, CA, USA. mimijl@mac.com
    • J Vet Emerg Crit Care (San Antonio). 2009 Jun 1; 19 (3): 262-8.

    ObjectiveTo describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock.Case SummaryA dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI.New Or Unique Information ProvidedThis case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.

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