• Yue-sheng Huang.
• Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, the Third Military Medical University, Chongqing 400038, PR China.
• Zhonghua Shao Shang Za Zhi. 2008 Jun 1; 24 (3): 161-3.

AbstractIt is well known that shock is one of the main complications occurring during early stage of severe burn, and presently, ischemic/hypoxic damage of tissues and organs is still hard to be prevented by various fluid resuscitation regimens. Findings in recent years demonstrated that postburn cardiac damage occurs promptly and much earlier than any other organs. Application of measures to ameliorate cardiac damage may improve organ blood flow in liver, kidney, and intestines, and mitigate organ damage concomitant with fluid resuscitation according to Parkland formula. These facts suggest that cardiac damage occurring promptly at early stage of severe burn is one of the important factors leading to ischemia/hypoxia of tissues and organs, therefore,new resuscitation regimen including "volume replacement" plus "dynamic support" may conduct to more effective burn shock resuscitation, and reduce organ complications as a result of either insufficient or over fluid infusion.

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