• Clin. Infect. Dis. · Mar 2009

    Comparative Study

    Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB.

    • Edward D Chan, Matthew J Strand, and Michael D Iseman.
    • Department of Medicine, National Jewish Health, Denver, CO 80206, USA.
    • Clin. Infect. Dis. 2009 Mar 1; 48 (5): e50-2.

    AbstractMultidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.

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