• Cardiovasc Intervent Radiol · Aug 2010

    Review

    Have recent vertebroplasty trials changed the indications for vertebroplasty?

    • Afshin Gangi and William A Clark.
    • Department of Nonvascular Interventional Radiology, University Hospital of Strasbourg, 67091 Strasbourg, France. gangi@rad6.u-strasbg.fr
    • Cardiovasc Intervent Radiol. 2010 Aug 1; 33 (4): 677-80.

    AbstractTwo different investigators in the New England Journal of Medicine recently published two randomized controlled trials (RCTs) regarding the efficacy of vertebroplasty for painful osteoporotic vertebral compression fractures. In their results, both investigators concluded that there was no significant difference in pain relief between the vertebroplasty group and control group 1 month after treatment. The trials described a different patient cohort from the one we treat with vertebroplasty. Both enrolled patients had back pain for 4 years for completion. We advise that vertebroplasty be offered to patients with recent fractures <8 weeks old who have uncontrolled pain as well as patients progressing to osteonecrosis and the intravertebral vacuum phenomenon (Kummels disease). The availability of recent MRI scanning is also critical to proper patient selection.

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