• Clinical pediatrics · Dec 1989

    Case Reports

    Peripheral limb gangrene following rectal biopsy. Treatment with prostacyclin and exchange transfusion.

    • B R Jani, R J Brereton, and M J Dillon.
    • Queen Elizabeth Hospital for Children, London, England.
    • Clin Pediatr (Phila). 1989 Dec 1; 28 (12): 585-8.

    AbstractAfter a rectal biopsy, a 3-week-old boy developed centripetally progressive distal limb gangrene. This was accompanied by transient hypertension and high levels of circulating immune complexes. The ischemia was reversed by prostacyclin infusion, oral corticosteroids and multiple exchange transfusions.

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