• BMJ case reports · Jan 2014

    West-African trypanosomiasis in a returned traveller from Ghana: an unusual cause of progressive neurological decline.

    • Ivo Elliott, Trupti Patel, Jagrit Shah, and Pradhib Venkatesan.
    • Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham, UK.
    • BMJ Case Rep. 2014 Jan 1; 2014.

    AbstractWest-African trypanosomiasis caused by Trypanosoma brucei gambiense is a rare imported infection presenting with somnolence, lymphadenopathy and wide-ranging neurological symptoms. A 67-year-old Caucasian man presented with a 10-month history of cognitive deterioration, ataxic gait, somnolence and urinary incontinence. His symptoms had progressed more rapidly over the course of a month prior to admission. Serological testing confirmed a diagnosis of West-African trypanosomiasis. The patient was successfully treated with eflornithine and made a good recovery. West-African trypanosomiasis should be considered in the differential diagnosis of unexplained cognitive decline in those with a relevant travel history. If left untreated, the condition is universally fatal.2014 BMJ Publishing Group Ltd.

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