• Clin. Lab. Med. · Dec 2014

    Review

    The changing landscape of the vaginal microbiome.

    • Bernice Huang, Jennifer M Fettweis, J Paul Brooks, Kimberly K Jefferson, and Gregory A Buck.
    • Department of Microbiology and Immunology, Center for the Study of Biological Complexity, 1101 East Marshall Street, PO Box 980678, Richmond, VA 23298, USA.
    • Clin. Lab. Med. 2014 Dec 1; 34 (4): 747-61.

    AbstractDeep sequence analysis of the vaginal microbiome is revealing an unexpected complexity that was not anticipated as recently as several years ago. The lack of clarity in the definition of a healthy vaginal microbiome, much less an unhealthy vaginal microbiome, underscores the need for more investigation of these phenomena. Some clarity may be gained by the careful analysis of the genomes of the specific bacteria in these women. Ongoing studies will clarify this process and offer relief for women with recurring vaginal maladies and hope for pregnant women to avoid the experience of preterm birth.Copyright © 2014 Elsevier Inc. All rights reserved.

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