• Curr Neurol Neurosci Rep · Mar 2016

    Review

    Tumefactive Demyelinating Lesions in Multiple Sclerosis and Associated Disorders.

    • Meredith C Frederick and Michelle H Cameron.
    • Department of Neurology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, L226, Portland, OR, 97239, USA. Frederim@OHSU.edu.
    • Curr Neurol Neurosci Rep. 2016 Mar 1; 16 (3): 26.

    AbstractTumefactive demyelinating lesions are rare consequences of central nervous system (CNS) idiopathic inflammatory demyelinating diseases. Tumefactive demyelinating lesions pose a diagnostic challenge because they can mimic tumors and abscesses and because they can be caused by a heterogeneous range of disorders. This article reviews the recent literature on the clinical presentation; radiographic features; prognosis; and management of tumefactive demyelinating lesions in multiple sclerosis, acute demyelinating encephalomyelitis, neuromyelitis optica, and the rare variants of multiple sclerosis including Schilder's disease, Marburg acute multiple sclerosis, and Balo's concentric sclerosis.

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