• JAMA · Mar 2015

    Comment

    Systemic corticosteroid therapy for acute sinusitis.

    • Roderick P Venekamp, Matthew J Thompson, and Maroeska M Rovers.
    • Division Surgical Specialties, Department of Otorhinolaryngology, University Medical Center Utrecht, the Netherlands2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.
    • JAMA. 2015 Mar 24;313(12):1258-9.

    Clinical QuestionAre oral or parenteral corticosteroids associated with improved clinical outcomes in patients with acute sinusitis compared with placebo or nonsteroidal anti-inflammatory drugs (NSAIDs)?Bottom LineOral corticosteroids combined with antibiotics may be associated with modest benefit for short-term relief of symptoms in adults with severe symptoms of acute sinusitis compared with antibiotics alone. Oral corticosteroids as monotherapy are not associated with improved clinical outcomes in adults with clinically diagnosed acute sinusitis.

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