• J Clin Anesth · Dec 2016

    Atropine and glycopyrrolate do not support bacterial growth-safety and economic considerations.

    • Balazs Ittzes, Zsolt Weiling, Istvan Zoard Batai, Monika Kerenyi, and Istvan Batai.
    • Department of Medical Microbiology, University of Pecs, Pecs, Hungary, Szigeti u. 12. H-7624. Electronic address: bittzes@hotmail.com.
    • J Clin Anesth. 2016 Dec 1; 35: 560-563.

    Study ObjectiveEvaluation of bacterial growth in atropine and glycopyrrolate.DesignLaboratory investigation.Subjects And MeasurementsStandard microbiological methods were used to evaluate the impact of atropine and glycopyrrolate on the growth of Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. Bacterial count was checked at 0, 1, 2, 3, 4, 6, and 24 hours.Main ResultsAtropine or glycopyrrolate did not support the growth of the above bacteria at any examined time at room temperature. Glycopyrrolate killed all of the examined strains (P < .05), whereas in atropine, only the clinical isolates of Staphylococcus and Acinetobacter were killed (P < .05).ConclusionsDrawing up atropine or glycopyrrolate at the beginning of the operating list and use within 24 hours if needed are a safe practice and do not pose infection hazard. We can also reduce hospital costs if we do not throw away these unused syringes following each case.Copyright © 2016 Elsevier Inc. All rights reserved.

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