• Liang Sun, Meng-Jiang Ding, Tian-Cai Cai, Hao-Jun Fan, Hong-Mei Gao, and Jian-Peng Zhang.
• Medical College of Chinese PLA, Chinese PLA General Hospital, 28#, Fu-Xing Road, Haidian District, Beijing 100853, China; Department of Respiratory and Critical Care Medicine of Ping Jin Hospital, Affiliated Hospital of Logistic University of Chinese People's Armed Police Force, China. Electronic address: sunlianghys@163.com.
• Am J Emerg Med. 2017 Oct 1; 35 (10): 1536-1541.

ObjectivesTo validate the effects of the new plateau hyperbaric chamber on alleviating high altitude hypoxia on Mount Kun Lun.MethodsA prospective, controlled study of rabbits and adult volunteers was conducted at altitudes of 355, 2880 and 4532m. We obtained arterial blood samples from rabbits and volunteers before and after hyperbaric treatment. The respiratory rate, heart rate, and blood pressure (BP) of adult volunteers were monitored during hyperbaric treatment.ResultsThe mean PaO2 levels of experimental group rabbits and volunteers increased significantly after 60min of hyperbaric treatment at 350, 2880 and 4532m. The mean PaCO2 and pH levels of rabbits were not significant different before and after hyperbaric treatment at each altitude. The mean PaCO2 and pH levels were not significant different at 355m in the human study. However, at 2880 and 4532m, pH fell with increasing PaCO2 levels in humans before and after hyperbaric treatment.ConclusionsThe new multiplace plateau hyperbaric chamber may be used to alleviate plateau hypoxia by increasing patient PaO2. However, its value in treating AMS must be confirmed in field conditions.Copyright © 2017. Published by Elsevier Inc.

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