• Eur. J. Paediatr. Neurol. · Jul 2011

    Case Reports

    Acute leukoencephalopathy after buprenorphine intoxication in a 2-year-old child.

    • Blandine Bellot, Fabrice Michel, Laurent Thomachot, Kathia Chaumoitre, Fabrice Battaglia, and Pierre Lagier.
    • Unité de Réanimation Pédiatrique et Néonatale et Brûlés Pédiatriques, Assistance Publique-Hôpitaux de Marseille, Centre Hospitalier Universitaire Nord, Chemin des Bourrely, 13915 Marseille, Cedex 20, France.
    • Eur. J. Paediatr. Neurol. 2011 Jul 1; 15 (4): 368-71.

    AbstractLeukoencephalopathies have been reported after heroin inhalation or ingestion, and buprenorphine injection, but the physiopathology remains unclear. We report here the first case of leukoencephalopathy caused by buprenorphine ingestion in a 2-year-old child who was admitted for coma and fever. Due to technical problems, the toxicology screen was delayed, and infectious disease was first suspected. A brain MRI found bilateral and symmetric white matter damages in the cerebral hemispheres and the cerebellum. Rapid recovery and positive toxicology screen for buprenorphine on day 4 confirmed the diagnosis of acute intoxication.Copyright © 2011 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…