• Cenk Sarı, Abdullah Nabi Aslan, Serdal Baştuğ, Murat Akçay, Nihal Akar Bayram, Emine Bilen, Hüseyin Ayhan, Hacı Ahmet Kasapkara, Tahir Durmaz, Telat Keleş, and Engin Bozkurt.
• Department of Cardiology, Ankara Ataturk Education and R esearch Hospital, Ankara, Turkey. cengaver61@yahoo.com.
• Cardiol J. 2016 Jan 1; 23 (4): 449-55.

BackgroundChronic increased afterload due to severe aortic stenosis (AS) results in com-pensatory concentric left ventricular (LV) hypertrophy and LV dysfunction. These in turn cause remodeling of the left heart. The aim of this study was to investigate the acute effect of transcatheter aortic valve implantation (TAVI) on left atrial (LA) mechanics and LV diastolic function.MethodsThe study consisted of a total of 35 consecutive patients (mean age was 77.7 ± 5.0 years, 25 female) undergoing TAVI. All TAVI procedures have been performed under the transesophageal echocardiography (TEE) guidance. Before and 24 h after TAVI, all patients underwent transthoracic echocardiography (TTE) and mitral inflow velocities with pulsed-wave (PW) Doppler including early filling wave (E), late diastolic filling wave (A), and E/A ratio were obtained. LV diastolic function was also explored by pulsed tissue Doppler imaging (TDI). Early (E') and late (A') diastolic annular velocities, E'/A' ratio and E/E' ratio were obtained. In addition, during the procedure before and minutes after the valve implantation, the left atrial appendage-peak antegrade flow velocity (LAA-PAFV) was measured and recorded with TEE.ResultsCompared with baseline, the mean mitral E, septal E' and E'/A' ratio increased significantly after TAVI. In addition, the LAA-PAFV increased significantly within minutes of TAVI (32.45 ± 10.7 cm/s vs. 47.6 ± 12.6 cm/s, p < 0.001).ConclusionsTAVI improves LV diastolic function and LA performance immediately.

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