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Pediatric emergency care · Dec 2020
Vascular Endothelial Growth Factor and Soluble Vascular Endothelial Growth Factor Receptor as Novel Biomarkers for Poor Outcomes in Children With Severe Sepsis and Septic Shock.
- Jane E Whitney, Melanie Silverman, Jackson S Norton, Richard G Bachur, and Elliot Melendez.
- From the Boston Combined Residency Program in Pediatrics, Boston Children's Hospital/Boston Medical Center.
- Pediatr Emerg Care. 2020 Dec 1; 36 (12): e715-e719.
AbstractVascular endothelial growth factor (VEGF) and its receptor, soluble fms-like tyrosine kinase (sFLT), are biomarkers of endothelial activation. Vascular endothelial growth factor and sFLT have been associated with sepsis severity among adults, but pediatric data are lacking. The goal of this study was to assess VEGF and sFLT as predictors of outcome for children with sepsis.
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