• Frédéric Lapostolle, Sophie Bataille, Aurélie Loyeau, Benoît Simon, François-Xavier Laborne, François Dupas, Thévy Boche, Lionel Lamhaut, Virginie Pirès, Hugues Lefort, Mireille Mapouata, Gaëlle Le Bail, Lisa Weisslinger, Jean-Michel Juliard, Yves Lambert, and e-MUST Registry Investigators.
• SAMU 93, UF Recherche-Enseignement-Qualité, Avicenne Hospital-APHP, Bobigny.
• Eur J Emerg Med. 2019 Dec 1; 26 (6): 423-427.

ObjectiveMortality in patients with ST-segment elevation myocardial infarction (STEMI) has been associated with the volume of activity of percutaneous coronary intervention (PCI) facilities. This observational study investigated whether the coronary reperfusion-decision rate is associated with the volume of activity in a prehospital emergency setting.MethodsProspectively collected data for the period 2003-2013 were extracted from a regional registry of all STEMI patients handled by eight dispatch centers (SAMUs) in and around Paris [41 mobile ICU (MICUs)]. A possible association between volume of activity (number of STEMIs) and coronary reperfusion-decision rate, and subsidiarily between volume of activity and choice of technique (fibrinolysis vs. primary PCI), were investigated. Explanatory factors (patient age, sex, delay between pain onset and first medical contact, and access to a PCI facility) were analyzed in a multivariate analysis.ResultsOverall, 18 162 patients; male/female 3.5/1; median age 62 (52-72) years were included in the analysis. The median number of STEMIs per MICU was 339 (IQ 220-508) and that of reperfusion-decisions was 94% (91-95). There was no association between the decision rate and the number of STEMIs (P = 0.1). However, the decision rate was associated with age, sex, delay, and access to a PCI facility (P < 0.0001) in a highly significant way. Fibrinolysis was a more frequent option for low-volume (remoter PCI facilities) than high-volume MICUs (30 vs. 16%).ConclusionThe decision of coronary reperfusion in a prehospital emergency setting depended on patient characteristics, delay between pain onset and first medical contact, and access to a PCI facility, but not on volume of activity. Promoting fibrinolysis use in underserved areas might help increase the reperfusion-decision rate.

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