• Pediatr. Clin. North Am. · Dec 2015

    Review

    Food Protein-Induced Enterocolitis Syndrome.

    • Stephanie A Leonard and Anna Nowak-Węgrzyn.
    • Division of Pediatric Allergy & Immunology, Rady Children's Hospital San Diego, University of California, San Diego, 3020 Children's Way, MC 5114, San Diego, CA 92123, USA.
    • Pediatr. Clin. North Am. 2015 Dec 1; 62 (6): 1463-77.

    AbstractFood protein-induced enterocolitis syndrome (FPIES) is a rare, non-immunoglobulin E-mediated gastrointestinal food allergy primarily diagnosed in infancy, but has also been reported in older children and adults. Acute FPIES reactions typically present with delayed, repetitive vomiting, lethargy, and pallor within 1 to 4 hours of food ingestion. Chronic FPIES typically presents with protracted vomiting and/or diarrhea, and weight loss or poor growth. Common foods triggering FPIES include cow's milk, soy, rice, oats, fish, and egg. More detailed diagnostic criteria may help in increasing awareness of FPIES and reducing delayed diagnoses or misdiagnoses. Copyright © 2015 Elsevier Inc. All rights reserved.

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