• Am J Emerg Med · Jul 2018

    Case Reports

    Refractory ventricular fibrillation in patient taking Lamictal.

    • Andrew Dream, Helena Holmgren, Rebecca Merrill, and Erin L Simon.
    • Cleveland Clinic Akron General, Department of Emergency Medicine, Akron, OH, United States.
    • Am J Emerg Med. 2018 Jul 1; 36 (7): 1324.e1-1324.e2.

    AbstractRefractory ventricular fibrillation occurs when there are three or more episodes of ventricular fibrillation within a 24-hour period. We report the first case of a 35-year-old woman without prior medical or family cardiac history who sustained refractory ventricular fibrillation while taking Lamictal for bipolar depression. She presented to the Emergency Department (ED) after a syncopal episode at work. She then sustained a cardiac arrest and required defibrillation in the ED multiple times due to recurrent ventricular fibrillation. The patient received a Subcutaneous Implantable Cardio-Defibrillator and was discharged home. There was no identifiable cardiac or medical cause of her ventricular fibrillation and the electrophysiologist suspected Lamictal caused her refractory ventricular fibrillation.Copyright © 2018 Elsevier Inc. All rights reserved.

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