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- Marshall Stephen Tenenbein and Milton Tenenbein.
- Department of Pediatrics and Child Health, University of Manitoba, Canada.
- Pediatr Emerg Care. 2005 Oct 1; 21 (10): 675-6.
BackgroundAntibiotic overdose is typically regarded as a benign event. We report a 15-year-old girl who developed pancreatitis after an overdose of erythromycin.CaseA 15-year-old girl presented for care because of severe epigastric pain after an overdose of 5.3 g (16 x 333 mg tablets) of erythromycin base. Her physical examination was normal except for epigastric tenderness. Her serum lipase was 2024 U/L (normal, <60). She was treated with intravenous fluids and an opiate analgesic. Her serum lipase declined to 1834 and 73 U/L at 17 and 36 hours, respectively, after the initial measurement at which time she was asymptomatic.ConclusionOur case supports transient pancreatitis as a potential consequence of erythromycin overdose.
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