• Journal of neurovirology · Feb 2017

    Case Reports

    Adult-onset opsoclonus-myoclonus syndrome due to West Nile Virus treated with intravenous immunoglobulin.

    • Julien Hébert, David Armstrong, Nick Daneman, Jennifer Deborah Jain, and James Perry.
    • Division of Neurology, University of Toronto, Toronto, ON, Canada.
    • J. Neurovirol. 2017 Feb 1; 23 (1): 158-159.

    AbstractA 63-year-old female with no significant past medical history was presented with a 5-day history of progressive opsoclonus-myoclonus, headaches, and fevers. Her workup was significant only for positive West-Nile Virus serum serologies. She received a 2-day course of intravenous immunoglobulin (IvIG). At an 8-week follow up, she had a complete neurological remission. Adult-onset opsoclonus-myoclonus syndrome is a rare condition for which paraneoplastic and infectious causes have been attributed. To our knowledge, this is the first case reported of opsoclonus-myoclonus secondary to West-Nile Virus treated with intravenous immunoglobulin monotherapy.

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