• Curr Pain Headache Rep · Feb 2002

    Review

    Ethical considerations in cluster headache research.

    • Stewart J Tepper, Alan M Rapoport, and Fred D Sheftell.
    • The New England Center for Headache, 778 Long Ridge Road, Stamford, CT 06902, USA. sjtepper@aol.com
    • Curr Pain Headache Rep. 2002 Feb 1; 6 (1): 47-51.

    AbstractCluster headache is the most painful of the primary headache disorders and elucidating pathophysiology and treatment for this disorder is crucial. There is justification for studying attacks untreated, and even for precipitating these attacks. Placebo-controlled studies should only be undertaken for regulatory purposes; otherwise, active control should be used.

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