Albumin Use in Brain-injured and Neurosurgical Patients:

J Neurosurg Anesthesiol · Oct 2021

Review

Albumin Use in Brain-injured and Neurosurgical Patients: Concepts, Indications, and Controversies.

Human albumin has been used extensively for decades as a nonwhole blood plasma replacement fluid in the perioperative and critical care setting. Its potential advantages as a highly effective volume expander must be weighed, however, against its potential harm for patients in the context of various neurological states and for various neurosurgical interventions. This narrative review explores the physiological considerations of intravenous human albumin as a replacement fluid and examines the extant clinical evidence for and against its use within the various facets of modern neuroanesthesia and neurocritical care practice.

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- Heung Kan Ma and John F Bebawy.
- Northwestern University Feinberg School of Medicine, Chicago, IL.
- J Neurosurg Anesthesiol. 2021 Oct 1; 33 (4): 293299293-299.
AbstractHuman albumin has been used extensively for decades as a nonwhole blood plasma replacement fluid in the perioperative and critical care setting. Its potential advantages as a highly effective volume expander must be weighed, however, against its potential harm for patients in the context of various neurological states and for various neurosurgical interventions. This narrative review explores the physiological considerations of intravenous human albumin as a replacement fluid and examines the extant clinical evidence for and against its use within the various facets of modern neuroanesthesia and neurocritical care practice.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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Albumin Use in Brain-injured and Neurosurgical Patients: Concepts, Indications, and Controversies.

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