• Eur J Ophthalmol · Sep 2004

    Case Reports

    Infliximab for the treatment of posterior uveitis with retinal neovascularization in Behçet disease.

    • F Giansanti, M L Barbera, G Virgili, B Pieri, L Emmi, and U Menchini.
    • Eye Clinic, Department of Oto-Neuro-Ophthalmological Surgical Sciences, University of Firenze, Firenze--Italy. fabriziogiansanti@interfree.it
    • Eur J Ophthalmol. 2004 Sep 1; 14 (5): 445-8.

    PurposeTo report a case of posterior uveitis with retinal neovascularization in a patient with Behçet disease treated with infliximab.MethodsA 50-year-old man with a history of recurrent relapses of ocular inflammation despite immunosuppressive therapy developed retinal neovascularization near the optic disk. The patient was treated with infliximab and followed up for 12 months.ResultsRetinal neovascularization regressed 8 months after the first anti-tumor necrosis factor (TNF) treatment and with six infusions of infliximab. The ocular inflammation resolved almost completely.ConclusionsThe result suggests that anti-TNF therapy may be effective in the treatment of retinal neovascularization caused by panuveitis in Behçet disease.

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