• Andrey V Cybulsky, Michael Walsh, Greg Knoll, Michelle Hladunewich, Joanne Bargman, Heather Reich, Atul Humar, Susan Samuel, Martin Bitzan, Michael Zappitelli, Allison Dart, Cherry Mammen, Maury Pinsk, and Norman Muirhead.
• Department of Medicine, McGill University, Montreal, Quebec.
• Am. J. Kidney Dis. 2014 Mar 1; 63 (3): 363-77.

AbstractThe KDIGO (Kidney Disease: Improving Global Outcomes) clinical practice guideline for management of glomerulonephritis was recently released. The Canadian Society of Nephrology convened a working group to review the recommendations and comment on their relevancy and applicability to the Canadian context. A subgroup of adult nephrologists reviewed the guideline statements for management of glomerular disease in adults and agreed with most of the guideline statements developed by KDIGO. This commentary highlights areas for which there is lack of evidence and areas in need of translation of evidence into clinical practice. Areas of controversy or uncertainty, including the choice of second-line agents, are discussed in more detail. Existing practice variation also is addressed. The relevance of treatment recommendations to the Canadian practitioner is discussed. Copyright © 2014 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

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