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Clinics in chest medicine · Mar 2015
ReviewEpidemiology of human pulmonary infection with nontuberculous mycobacteria: a review.
- D Rebecca Prevots and Theodore K Marras.
- Epidemiology Unit, Laboratory of Clinical Infectious Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 9000 Rockville Pike, Building 15B-1, 8 West Drive, MSC 2665, Bethesda, MD 20892, USA. Electronic address: rprevots@niaid.nih.gov.
- Clin. Chest Med. 2015 Mar 1; 36 (1): 13-34.
AbstractPopulation-based data have documented a worldwide increase in the prevalence of human nontuberculous mycobacterial (NTM) infections since 2000. Mycobacterium avium complex is predominant in North America and East Asia, whereas in regions within Europe, M kansasii, M xenopi, and M malmoense are more common. Host factors important to the current epidemiology of NTM pulmonary disease include thoracic skeletal abnormalities, rheumatoid arthritis, and use of immunomodulatory drugs. Clustering of disease within families suggests a heritable genetic predisposition to disease susceptibility. Warm, humid environments with high atmospheric vapor pressure contribute to population risk. Published by Elsevier Inc.
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